Check out these publishing charms for first time, unagented, and (potentially) published authors:
Blue Moon Publishers publishes literary fiction, women’s fiction, YA, middle grade, contemporary, historical, mystery, suspense, thriller, SciFi, fantasy, and humor. Bonus points for stories that have series potential! Read the specs and send a proposal here.
Quirk Books quirkifies "smart, original, cool, and fun" manuscripts, as long as they're quirky! Check out the quirky editors and submit here.
Talos Press presses science fiction, fantasy, and horror. Flip through their website, then propose your book here.